#513 Standardized high-sensitivity Hispano-American language tests for epilepsy and brain tumor patients before, during, and after surgery
Andrés Felipe Reyes, Luisa Fernanda Jaimes, Luis Fernando Alvarado Zuñiga, Diana Leal, Enrique Osorio
Clinical Neurophysiology, 191, 2112228
Resumen
Preserving language is critical during functional brain surgery, and neurophysiologists often perform this assessment. However, while postoperative performance is generally reported as positive, several studies suggest otherwise. Despite language involving so much more than just automatic tasks and naming, intraoperative objective assessments are often limited to counting and object naming, which assess insufficient linguistic levels. Preoperative tests also lack control for both surgical and linguistic variables or are not sensitive enough to detect mild impairments, leading to an overestimation of the patient's baseline and making language preservation during surgery unreliable. We present a 100-image battery with two stimulus sets that elicit verb and noun production. We performed a naming analysis to establish picture-name agreement scores, digital surveys to collect data on imageability and age-of-acquisition, and additional pertinent linguistic factors. Both sets were normalized with healthy participants closely matching the age of onset for epilepsy and brain tumors (x̅ = 21.7 and x̅ = 52.7 years respectively; n = 100 each). Both stimulus sets demonstrate over 80% name agreement alongside strong internal consistency/reliability and are calibrated for psycholinguistic parameters that influence lexical retrieval. We illustrate our work with a clinical case that includes diagnostic imaging. This battery will enhance the validity and reliability of the neurophysiologists' work.